Oprah Winfrey Calls it Quits, Prompts Speculation About a Replacement

She has been one of the family for Americans for 25 years," Tina Brown, founder and editor-in-chief of The Daily Beast told "Good Morning America" today. "The audience is just going to have to follow her, right?"

But where Winfrey will go from here remains to be seen. Winfrey notified her staff late Thursday afternoon that she would be ending her talk show on Sept. 9, 2011, just as the show will mark 25 years on the air. The meeting, insiders say, was "emotional, supportive and respectful."

Oprah Winfrey Calls it Quits, Prompts Speculation About a Replacement